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Human clinical trials show an improvement in 2/16 hydroxy-estrone ratios in women taking I3C, demonstrating its value in helping lower risk in these women.
The proper processing of estrogen metabolites requires folic acid. Folic acid deficiency, especially alcohol-related, increases risk for estrogen-related breast conditions. Men’s Health
I3C is considered one of the main active ingredients accounting for the health benefits found in cruciferous vegetables. I3C, and many of its metabolites including DIM, have been investigated with in vitro, animal and human studies.
The proper processing of estrogen metabolites requires folic acid. Folic acid deficiency, especially alcohol-related, increases risk for estrogen-related conditions effecting the prostate.
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