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Glucosamine Chondroitin MSM 120 Capsules

Item # DRB1118
Regular Price: $25.99Our Price: $13.61
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Glucosamine Chondroitin MSM 120 Capsules
Glucosamine Chondroitin MSM 120 CapsulesGlucosamine Chondroitin MSM 120 CapsulesGlucosamine Chondroitin MSM 120 Capsules

Product Q & A
MFG # DRB-00080
UPC # 753950000803
Official Website: http://www.drbvitamins.com

Science-based nutrition
Dietary supplement
Maintains healthy joints and connective tissue

Contains sodium-free potassium stabilized glucosamine sulfate‚ bovine chondroitin sulfate and pure MSM. (OptiMSM®).


Supports Joint Structure‚ Function‚ and Comfort

The Roles of Glucosamine and Chondroitin Sulfate in Joints
Articular cartilage is a connective tissue composed of specialized cells (chondrocytes) embedded in a matrix of protein fibers (mostly collagen) and clusters of complex proteoglycan molecules that consist of a protein core with numerous side chains. These side chains‚ chiefly chondroitin sulfate and keratin sulfate‚ are long polysaccharide molecules called glycosaminoglycans. Chondroitin sulfate (CS) and the other glycosaminoglycans strongly attract water due to the negative charges of their sulfate groups. These negative charges also repel each other‚ creating spaces between glycosaminoglycan side chains where water can enter. This combination of solid and liquid gives cartilage a compressible quality that allows it to function as a shock absorber for joints.

Glucosamine is a fundamental building block for proteoglycans and glycosaminoglycans. Glucosamine sulfate (GS) helps to maintain joint health through its ability to both act as a component of and stimulate formation of cartilage glycosaminoglycans and the hyaluronic acid backbone essential for the formation of cartilage proteoglycans.

The Abundant Evidence Behind Glucosamine and Chondroitin Sulfate
Extensive joint health research over the past few decades has investigated the effects of glucosamine sulfate‚ chondroitin sulfate‚ or a combination of the two. A 2009 meta-analysis summarized results from 6 well-designed studies involving a total of 1‚502 research participants. The authors of this meta-analysis were able to make some conclusions about the apparent effectiveness of long-term oral supplementation with CS or GS. Glucosamine sulfate at 1‚500 mg daily over a period of at least 3 years and chondroitin sulfate at 800 mg daily over a period of at least 2 years both helped subjects maintain healthy knee cartilage structure.3 In a 2008 review of GS & CS used for joint support‚ the London physician who wrote it concludes that‚ “Glucosamine‚ chondroitin‚ and the combination of these two agents have stood the test of time.”

Glucosamine sulfate is one of the most important—and thoroughly researched—dietary supplements for joint health ever developed. In addition to its potential to influence joint structure (and thus function)‚ research also backs the ability of GS to influence joint comfort. In one such multicenter‚ randomized‚ double-blind‚ parallel-group study of 252 subjects‚ joint comfort in the knee was found to be higher in the glucosamine sulfate group than the placebo group.6 Similar studies of equal magnitude found that GS enhanced joint comfort. Key among findings from these types of studies is the reoccurring theme of a good safety profile for glucosamine sulfate; reported “side effects” of GS were essentially no different than placebo.

Similar to glucosamine‚ chondroitin sulfate is known to influence the maintenance of healthy cartilage—in this case by acting on matrix metalloproteases (MMPs). Chondroitin sulfate has been shown to inhibit MMP-3 synthesis‚ which plays an important role in homeostasis of cartilage proteoglycans. Additionally‚ CS can downplay MMP-13 in chondrocytes‚ helping to maintain the integrity of articular cartilage matrix.

Clinical Trials Explore MSM’s Joint Action
Results from a randomized‚ double-blind‚ placebo-controlled pilot trial examining the effect of MSM supplementation on joint comfort in 50 men and women are promising. Subjects taking OptiMSM® methylsulfonylmethane for 12 weeks experienced greater joint comfort than those taking placebo‚ suggesting potential for MSM as a joint support nutrient that warrants further investigation in larger clinical trials. MSM also produced statistically significant changes in urinary malondialdehyde‚ a marker of oxidative stress.

MSM has also been used in combination with glucosamine to study their impact on the health of joints. In one such study‚ a total of 118 subjects were randomized into one of four groups for 12 weeks: glucosamine (500 mg three times daily)‚ MSM (500 mg three times daily)‚ the combination of glucosamine and MSM‚ or a placebo treatment. Glucosamine alone and MSM alone were shown to enhance joint function‚ while the combination was found to be even more effective‚ by both subjective and objective measurements.

These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose‚ treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition.

Serving Size: 2 Capsules
Serving per container: 60 servings

Amount Per Serving % DV

Chloride (from glucosamine sulfate 2KCl) 84 mg 2%
Sodium (from chondroitin sulfate) 28 mg 1%
Potassium (from glucosamine sulfate 2KCl) 91 mg 3%
Glucosamine sulfate 2KCl 750 mg †
Chondroitin sulfate 600 mg †
(from chondroitin sulfate sodium)
Methylsulfonylmethane 500 mg †
* Percent Daily Values based on a diet supplying 2000 calories per day.
† Daily Value not established.

Other ingredients: Cellulose‚ magnesium stearate (vegetable source)‚ gelatin (capsule).

Note: Glucosamine is obtained from the shells of shellfish. Contains sodium-free potassium stabilized glucosamine sulfate‚ bovine chondroitin sulfate plus pure MSM (OptiMSM®).

Contains nothing other than listed ingredients.

Does Not Contain: milk‚ egg‚ wheat‚ gluten‚ corn‚ soy‚ sugar‚ sweeteners‚ starch‚ salt‚ or preservatives.

Take 2 capsules twice daily‚ with or without food.

Glucosamine is obtained from the shells of shellfish.

Glucosamine Chondroitin MSM 120 Capsules
4.5 Stars based on 6 Review(s)
4/5 Stars
I would recommend this item to a friend.

Affordable and so good for... my neck!
March 25, 2014
I take 2 of these every day and my neck and shoulder pain is ancient history. Actually, they're so well-priced I give them to my dog too (a reduced dosage, approved by my vet). He's 12 years old and getting on... and so am I... :) Thanks PureFormulas for right-price products and the fastest (free!) delivery times on Planet Earth!

Lacey. Wa
5/5 Stars
I would recommend this item to a friend.

My docter told me this brand is just great that the company is huge and can afford to price low
August 23, 2013
I have re-ordered Glucosamine Chondroitin MSM 3 times. The doctor said capsules are more easily assimilated than tablets. And in addition to the already low price there is an extra 15% off on doctors best products.
price and quality

5/5 Stars
I would recommend this item to a friend.

Great if you work out
April 8, 2013
Glucosamine Chondroitin MSM is a necessity if you exercise often to help repair your joints/ligaments.

Crown Point, IN 46307
5/5 Stars
I would recommend this item to a friend.

March 2, 2013

elk river, MN
3/5 Stars
I would recommend this item to a friend.

Too early to tell
December 4, 2012
I have arthritis in my hands and have started again on Glucosamine Chondroitin MSM. I think it is better but not sure quite yet. As far as service you guys are great! Overall, everything is good except I wish we knew how much we should be taking for different ailments etc.

Eugene, OR
4/5 Stars
I would recommend this item to a friend.

works great for joint discomfort.
November 15, 2012
Naturpathic dr prescribed and I have been using them for 2-3 years. Joints feel better.

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