Pure L-Threonine 500 mg - 100 Capsules

WHAT IS THREONINE?
Get the benefits of Threonine - the essential amino acid that can't be produced by the body - by consuming it through your diet or supplement intake. Threonine is critical for proper protein balance and function, as well as the Kreb's cycle. It was the last amino acid that was discovered to be vital for protein biosynthesis back in 1935. Unfortunately, only a small amount of Threonine can be found in grains, which can lead to its deficiency, especially for vegetarians or individuals on a low-protein diet. Not having enough Threonine may result in irritability. Thankfully, Montiffs All-Basic, Gluca-Balance, and Super-Sports Amino Acid Formulas has included Threonine in its ingredients. This critical nutrient also has lipotropic features that assist in avoiding fatty deposits in the liver. It's also believed to have a potential effect on Methionine and Aspartic Acid, assisting in the prevention of fatty liver, which is characteristic in low protein diets. Threonine is a precursor for Glycine and is present in your heart, central nervous system, and skeletal muscles. It enhances the immune system by producing antibodies, helping us fight off illness. It's even potentially beneficial for individuals with ALS and MS.

THREONINE AND ALS (Amoytrophic Lateral Sclerosis or Lou Gherig's Disease) WHAT IS ALS ?
ALS, also known as Lou Gehrig's disease, is a fatal neurological condition that affects muscle control and causes progressive symptoms such as weakness, atrophy, cramps, and difficulty with speaking and swallowing. Over 4000 people are diagnosed with ALS in the US each year, mainly between ages 40 and 70. While the illness typically causes death in 2-4 years, some patients live significantly longer, with 5% surviving 10 years or more. In 1993, researchers identified a gene that causes ALS in some cases. This gene can lead to free radical damage, which results in the degeneration of an enzyme called superoxide dismutase. In other cases, a metabolic defect in the central nervous system affecting the motor neurons may be responsible. Studies have found that excessive levels of excitatory amino acids, such as aspartate and glutamate, play a role in ALS. Conversely, a decrease in Glycine in the central nervous system has also been noted. While it has been hypothesized that increasing Glycine levels could be beneficial, administering this amino acid is ineffective since it does not cross into the central nervous system. However, Threonine is a precursor to Glycine and may be effective in reducing some symptoms since it can cross into the CNS. Pyridoxal 5'Phostphate is necessary for the conversion of Threonine to Glycine. The devastating impact of ALS highlights the need for continued research into effective treatments for this debilitating disease.

THREONINE AND ITS EFFECT ON ALS
• Dr. B. Patten, at Baylor Univ. College of Med., 1988, administered between 2-4 grams of Threonine to 15 patients daily for 10 months. Improvement occurred within 48 hours of treatment, including better voice, less drooling, decreased fasciculations, increased energy and swallowing and decreased spasticity. Of the 15patients studied, 7 made definite improvements, 3 made minor improvements, and 5 remained unchanged. The greater the severity of symptoms of thesepatients, the more dramatic the improvements were noted. Some researchers have subsequently studied Threonine with varied and sometimes inconclusive results.
• Threonine supplementation appears to be most effective when given before significant neuronal damage occurs. Since active B-6 is necessary to convert Threonine to Glycine, Pyridoxal 5'Phospate is suggested, and a B complex in a capsule with P 5'P would be recommended (the contents may be emptied and mixed in a drink or easily consumed foods, if necessary). Also high quality, pure Threonine should be taken in encapsulated form, or powder for easier swallowing. Threonine should not be taken with protein or competitive amino acids such as Tyrosine, Phenylalanine, Tryptophan, Alanine and Serine, as well as the branched-chain amino acids,
Leucine, Isoleucine, Valine, since they may inhibit the uptake of Threonine into the brain.
• MULTIPLE SCLEROSIS (MS) is another neuro-muscular disease that Threonine may have an effect on. In double crossover study at Mass. Gen. Hospital, 1992, a dose of 7.5 grams daily was administered to 26 MS patients who showed a decrease of spasticity.

These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose‚ treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition.