Fully Active B Complex with Quatrefolic® - 30 Veggie Capsules

by Doctor's Best
  • 4.6
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"Great energy!"  Read all reviews

Item Number: DRB1180
Serving Size: 1 Capsule Servings per Container: 30
Price per Serving:  $0.36 Price per Unit*: $0.36 per Capsule
* Price Per Unit may reflect product's price per capsule, tablet, ounce, fluid ounce, etc.
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Helps support energy production and cell metabolism!

What is Doctor’s Best Fully Active B Complex?
Doctor’s Best Fully Active B Complex provides energy and helps coping with stress. B vitamins are needed to make energy from foods‚ and to make and maintain DNA‚ genes‚ cells‚ tissues‚ organs‚ and enzyme functions. B vitamins are fundamental to life‚ and humans cannot make them‚ therefore we need to get them through the diet. Doctor’s Best Fully Active B Complex provides only the best-utilized B vitamin forms. This includes fully active folate‚ the body’s most fully active folate and MTHF (methyl-tetra-hydro-folate). The Fully Active B Complex also provides fully active vitamin B12 as methylcobalamin (methyl-B12) to help ensure excellent oral absorption.

How does it work?
Best Fully Active B Complex is a full-spectrum B vitamin supplement‚ carefully designed for optimal absorption and utilization. This formulation provides the B vitamins in their safest‚ best tolerated‚ and most biochemically active forms. Thiamin (“Vitamin B1”) is fundamental to human metabolism because it is essential for the metabolism of oxygen. The microscopic “power plants” of our cells (mitochondria) require thiamin to generate energy. Riboflavin (“Vitamin B2”) is a cofactor for various mitochondrial enzymes and therefore essential for the body to make energy. Riboflavin is a necessary cofactor for the metabolism of homocysteine‚ a normal product of metabolism that can become toxic as it accumulates; and for the utilization of glutathione‚ a major antioxidant. Riboflavin also supports important enzymes that recycle folate and activate vitamin B6. Niacin and Niacinamide (“Vitamin B3”). This vitamin is fundamentally essential for numerous enzymes that make and use energy. Both niacin and niacinamide are readily activated to the cofactors that power these enzymes. Vitamin B6 (as pyridoxine hydrochloride and pyridoxal-5-phosphate). This vitamin is essential for at least 112 enzymes that metabolize carbohydrates‚ amino acids‚ and fatty acids—some 3% of all the known human enzymes. It is also essential for routing potentially harmful homocysteine along the “trans-sulfuration” pathway to produce glutathione and other important sulfur antioxidants. Vitamin B6 is vital for early brain development and for the metabolism of various brain chemical transmitters. Nerve cells both in the brain and elsewhere in the body rely heavily on B6. Certain neuroleptic drugs may impair the brain’s B6 utilization and increase dietary B6 requirements. Folate (as methyl-tetra-hydro-folate or MTHF‚ Quatrefolic®). This vitamin is a major dietary source of methyl groups‚ which are essential for a number of enzymes that make DNA‚ repair damaged DNA‚ and regulate gene activity via epigenetic actions. Folate’s central importance for such “housekeeping” functions make it crucial to the health of all our cells‚ tissues‚ and organs. Folate is also crucial for a healthy pregnancy. Vitamin B12 (cobalamin)‚ as methylcobalamin (methyl-B12). This vitamin works very closely with folate to support methyl metabolism and recycle homocysteine. The absorption of B12 from foods is highly dependent on a healthy gastrointestinal tract‚ is highly vulnerable to many over-the-counter and prescription medications‚ and tends to decline with age. Biotin This B vitamin is incorporated into the molecular structure of at least five enzymes called carboxylases that are widely involved in energetics‚ fat metabolism‚ and the metabolism of branched-chain amino acids important for many protein functions. Mitochondria require biotin for their energy functions (together with all the other B vitamins).



These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose‚ treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition.

  • MFG # DRB-00299
  • UPC # 753950002999
Official Website: http://www.drbvitamins.com

Serving Size: 1 Veggie Capsule
Servings Per Container: 30

Amount Per Serving / % DV

Vitamin C (As Ascorbic Acid) 40mg / 45%
Vitamin B1 (From Thiamin HCI) 60mg / 5000%
Vitamin B2 (From Riboflavin and Riboflavin-5-Phosphate) 75mg / 5770%
Vitamin B3 (As Niacinamide and Niacin) 50mg / 310%
Vitamin B6 (From Pyridoxine HCI and Pyridoxal-5-Phosphate) 50mg / 2940%
Folate 400mcg DFE** / 100%
(From Quatrefolic®‚ (6S)-5-methyltetrahydrofolic acid‚ glucosamine salt)
Vitamin B12 (As Methylcobalamin) 1000mcg / 41670%
Biotin 600mcg / 2000%
Pantothenic Acid (From D-Calcium Pantothenate) 100mg / 2000%

**DFE = Dietary Folate Equivalent.

Other Ingredients: Modified cellulose (vegetarian capsule)‚ microcrystalline cellulose‚ magnesium stearate (vegetable source)‚ silicon dioxide.

Non-GMO / Gluten-Free / Soy-Free / Vegan / Vegetarian.


Take 1 capsule daily with food‚ or as recommended by a nutritionally informed physician.


Store in a cool dry place.


  • Dairy Free
  • Gluten Free
  • GMO Free
  • Soy Free
  • Vegan
  • Vegetarian

Ratings and Reviews

Write a Review
  • 4.6
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5 26
  • 26 Reviews
    • Verified Buyer

      Can’t live without it!

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      from Irondale, AL on 3/08/2020
      Great energy!
      I would recommend this item to a friend.
    • Verified Buyer

      Excellent product

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      from Phoenix AZ on 10/13/2019
      I took this product for years and it worked great for me. Gave me more energy during the day.

      Pros

      Works well.

      Cons

      I stopped taking this product once I became aware of fillers and binders. Since I take handfuls of tablets every day, the bad fillers and binders started to add up. I now attempt to choose products without filler and binders. This one has magnesium stearate and silicon dioxide.
      I would recommend this item to a friend.
    • Verified Buyer

      Love this

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      from Okla on 11/07/2018
      When I first took this I gave it a bad review. The first day, the niacin made me feel sunburnt but the next day and since, it’s been fine. I like that it’s methylated so easy to absorb. If you have the MTHFR gene this is a good b complex for you.

      Pros

      Everything

      Cons

      Nothing
      I would recommend this item to a friend.
      1 of 1 people found the following review helpful.
    • Verified Buyer

      Great Product!

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      from Mount Juliet TN on 9/10/2018
      Love Fully Active B Complex by Doctor's Best! It has the correct form of B's for those with the MTHFR mutations.
      I would recommend this item to a friend.
    • Verified Buyer

      Great quality product!

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      from JONESBOROUGH TN on 2/19/2018
      Fully Active B Complex with Quatrefolic by Doctor's Best assists in overall energy level and metabolic processing.

      Pros

      Better energy level.

      Cons

      Nothing.
      I would recommend this item to a friend.
    • Verified Buyer

      Good stuff!

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      from Arlington MA on 2/07/2018
      I love Fully Active B Complex with Quatrefolic by Doctor's Best since I feel more refreshed after a nights sleep and maybe they make my dreams more memorable!

      Pros

      Makes me feel good.

      Cons

      Small amount of pills.
      I would recommend this item to a friend.
    • Verified Buyer

      Satisfied

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      from Las Vegas NV on 10/30/2017
      Best Fully Active B Complex by Doctor's Best a good quality product. It's the best I've used.

      Pros

      It's high potency.

      Cons

      None
      I would recommend this item to a friend.
    • Best and only b complex I would take

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      from Minneapolis on 6/22/2017
      Tried a lot b complex and individual b's over the years mainly to help with energy but nothing compares to this Best Fully Active B Complex by Doctor's Best. No strange or off feelings when taking it either-like most synthetic vitamins and mineral supplements! The activated forms are really the only way to go with b vitamins. Only downside perhaps is overloaded with b-12. Only take a few times per week because of that.

      Pros

      Activated forms

      Cons

      Too much B-12
      I would recommend this item to a friend.
    • Verified Buyer

      Best fully active B Complex

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      from Rollinsford, NH on 5/15/2017
      Best Fully Active B Complex by Doctor's Best is a new item for me. I was using the fully active B12, but had to decrease the amount I was using as my blood levels were on the toxic side. I will be using this for a month, get new bloodwork done and can provide an update then. It's a good idea to check with your doctor first before taking supplements.

      Pros

      Increase energy level, helps with nerve pain.

      Cons

      None 
      I would recommend this item to a friend.
    • Verified Buyer

      Great formulation

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      from TN on 5/11/2017
      The formulation of Best Fully Active B Complex by Doctor's Best is the best in quality and pricing.

      Pros

      The formulation as opposed to other brands.

      Cons

      Nothing
      I would recommend this item to a friend.
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Customer Questions and Answers

1-2 of 2

  • Question:
    What Is The Product In All The Supplements That Contains A Chemical Known To The State Of California To Cause Cancer, Birth Defects Or Other Reproductive Harm. I Have Seen This Warning For The Supplements That I Purchase,Even Though I Do Check All Of The Added Ingredients, I Also Make Sure It's Non GMO. Yet This Warning Always Comes -Up.
    Cathyanna Rossi on 3/04/2016 Answer:
    • Hi there Cathyanna! Proposition 65 is a study that the state of CA did to inform their residents of some ingredients (more than 800). All products sent to the state of CA gets this message on all the items unless otherwise directed by manufactures. It does not mean that any of the items have any chemical that will cause cancer or birth defects. You can contact the manufacture for more details whether or not it has any of the ingredients in it. All manufactures are aware of Proposition 65. 
      PureFormulas on 3/04/2016
  • Question:
    Doctor's Best Active B Complex: I thought I read somewhere that this would go rancid if sitting around too long. Is that why they are only available in 30 count? Would it be OK to order two bottles and keep them in the refrigerator?
    Lisa M Landfried on 7/19/2015 Answer:
    • Thank you for reaching out to us, Lisa. This product has a two year shelf-life. Doctor's Best products should be stored in dry conditions, out of areas that are humid such as a bathrooms or kitchens. Opening and closing a supplement bottle in these areas may allow moisture to be trapped in the bottle. Keep out of direct sunlight and cold unless otherwise labelled to refrigerate.
      PureFormulas on 7/23/2015

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